Library · Molecule

Antibody

Make it clearer

Antibodies are defense proteins made by cells called B cells. Their other name, the one used in the lab, is immunoglobulins: it's the same thing said with the technical word, not two different molecules.

What makes an antibody work against one thing and not another is its hypervariable regions, stretches of the molecule that vary enormously from one antibody to the next. Those stretches are what build the antigen-binding site, the pocket where whatever the antibody recognizes fits in. It's the logic of a key: the body can look much the same from one key to the next, but the pattern cut into the tip is what decides which door it opens.

In brief

Antibodies are immunoglobulins produced by B cells.

The hypervariable regions of these antibodies form the antigen-binding site.

The hypervariable regions meet at one surface where the antibody contacts its antigen.

Sources (1)
  1. NCBI BookshelfB Cells and AntibodiesPublished

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