Library · Histology

Endometrial histology

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Endometrial histology describes how the tissue is arranged. Epithelium covers the surface, glands extend downward, and supporting tissue called stroma surrounds them. Picture soft ground crossed by many narrow tubes: the tubes are the glands, and the ground is the stroma.

The superficial portion forms the stratum functionalis and changes during the cycle. Deeper down is the stratum basalis, which remains in place and helps regenerate the surface layer.

In brief

Endometrial histology includes epithelium lining the uterine cavity, tubular glands, and stroma containing fibroblast-like cells. Together, these components form a mucous membrane rather than a layer of muscle.

The tissue is divided into the stratum functionalis, near the cavity and subject to cyclic changes, and the deeper, regenerative stratum basalis. The proportion and appearance of glands and stroma vary with the hormonal phase while remaining parts of the same endometrium.

Sources (3)
  1. U.S. National Library of MedicineHistology of the human endometrium: from birth to senescence
  2. National Center for Biotechnology InformationUterine stem cells
  3. National Center for Biotechnology InformationPhysiology, Uterus

This page explains the topic in general terms; it does not tell anyone what treatment to follow.

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