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Gallbladder histology

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The gallbladder wall has an inner layer called the mucosa. Its simple columnar epithelium consists of tall cells with microvilli, tiny projections that face the bile. Picture a lining covered with fine bristles, increasing the contact surface.

These cells remove water and electrolytes, leaving the bile more concentrated. Farther out are irregular smooth muscle and connective tissue. The wall does not follow exactly the same layered pattern as the intestine.

In brief

The inner gallbladder wall is a mucosa lined by simple columnar epithelium. These cells have apical microvilli facing the bile and rest on a lamina propria made of connective tissue.

The microvilli absorb water and electrolytes, concentrating the bile inside the cavity. Beneath the mucosa are irregular smooth muscle and outer connective tissue. The gallbladder wall does not reproduce the typical layers of the intestine exactly.

Sources (1)
  1. National Center for Biotechnology InformationAnatomy, Abdomen and Pelvis: Gallbladder

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