Library · Histology
Lymph Node Histology
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A lymph node does not look like a uniform mixture under the microscope. Picture several neighborhoods within the same structure: follicles in the cortex are where B cells gather, the paracortex contains mostly T cells, and the medulla has cords and sinuses with many plasma cells.
When a follicle responds to antigens, it can become a secondary follicle with a germinal center surrounded by a mantle zone.
In brief
The lymph node is organized into zones: follicles in the cortex contain mostly B cells, the paracortex is a T-cell zone, and the medulla contains cords and sinuses rich in plasma cells.
Picture a lymph node divided into cellular neighborhoods, each with its own predominant immune cell populations.
When a follicle responds to antigens, it can become a secondary follicle with a germinal center and a mantle zone of mature B lymphocytes.
Sources (1)
- National Center for Biotechnology InformationHistology, Lymph NodesPublished
This page explains the topic in general terms; it does not tell anyone what treatment to follow.
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