Library · Histology

Olfactory epithelium

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The olfactory epithelium is the tissue you smell with. It is an epithelium, that is, a layer of cells that covers a surface, but a specialized one, and it sits in the upper back part of each nasal cavity, not at the entrance of the nose. That is where the cell bodies of the bipolar olfactory neurons live, the neurons that detect smell.

Each of those neurons ends in cilia, extremely fine projections, and the receptors that recognize the odor molecules, called odorants, sit on those cilia. Each neuron makes a single type of receptor. Bowman glands also secrete a fluid that helps dissolve the odorant. The odor particles dissolve in that fluid.

Then the signal leaves the nose. The axons, the cables of these neurons, cross the cribriform plate, a sheet of bone perforated like a sieve that separates the nose from the brain, and reach the olfactory bulb, where they gather into small clusters called glomeruli.

In brief

The olfactory epithelium is the specialized epithelial tissue of the posterosuperior portion of each nasal cavity, where the cell bodies of the bipolar olfactory neurons sit.

There, odorant molecules meet the receptors on the cilia of those neurons, and each neuron expresses a single receptor type.

Bowman glands secrete a fluid that helps dissolve the odorant, and the axons cross the cribriform plate and converge on glomeruli in the olfactory bulb.

The odor particles dissolve in that fluid.

Sources (2)
  1. National Center for Biotechnology Information, StatPearls PublishingNeuroanatomy, Cranial Nerve 1 (Olfactory), StatPearlsPublished
  2. National Center for Biotechnology Information, StatPearls PublishingPhysiology, Olfactory, StatPearlsPublished

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