Library · Neoplasm

Ovarian sex cord-stromal tumor

Make it clearer

Ovarian sex cord-stromal tumors begin in cells involved in the ovary's support and hormonal functions. They may be benign or malignant. Picture a family with several last names: granulosa, Sertoli, Leydig, and theca describe different forms of cell differentiation within the group.

These are not tumors of the surface epithelium or germ cells. Some produce sex hormones, while others do not do so in the same way. A shared cell family does not mean identical behavior.

In brief

Ovarian sex cord-stromal tumors are a family of benign or malignant neoplasms arising from the ovary's supporting cells and cells showing gonadal differentiation. They do not arise from the surface epithelium or from germ cells.

The family includes tumors showing granulosa, Sertoli, Leydig, or theca cell differentiation, among other stromal components. Some release sex hormones, but this ability varies across the group. The name joins related cellular origins, not a single biological behavior.

Sources (2)
  1. National Center for Biotechnology InformationOvarian sex cord-stromal tumor
  2. National Cancer InstituteDefinition of sex cord-stromal tumor

This page explains the topic in general terms; it does not tell anyone what treatment to follow.

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