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Splenic macrophage

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In splenic cords and sinuses, macrophages respond to antigens and filter abnormal or aging red blood cells. Their location places them in contact with blood moving through these structures.

Red-pulp macrophages also specialize in recycling iron from aged or damaged red blood cells. Removing an altered cell therefore allows some of its material to be recovered.

In brief

In splenic cords and sinuses, macrophages respond to antigens and filter abnormal or aging red blood cells.

Red-pulp macrophages specialize in recycling iron from aged or damaged red blood cells.

Removing an altered red blood cell also allows some of its iron to be recycled.

Sources (1)
  1. National Center for Biotechnology InformationPhysiology, Spleen

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