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Synoviocyte

Make it clearer

The synovial lining is a layer of cells at the boundary between joint tissue and the joint cavity. Think of it as an active border with two kinds of cells.

Type A cells belong to the same family as macrophages, cells that engulf debris. Type B cells come from fibroblasts and release protective synovial fluid into the cavity. One type removes material from the cavity; the other adds fluid.

In brief

Synoviocytes are the cells that form the synovial lining inside a joint. Type A synoviocytes come from the macrophage lineage and engulf debris to clear it from the joint cavity.

Type B synoviocytes are derived from fibroblasts and secrete protective synovial fluid into the joint cavity.

Sources (2)
  1. Iwanaga T, Shikichi M, Kitamura H, Yanase H, Nozawa-Inoue K; Archives of Histology and CytologyMorphology and functional roles of synoviocytes in the jointPublished
  2. Kolker SJ et al.; Annals of the Rheumatic DiseasesAcid-sensing ion channel 3 expressed in type B synoviocytes and chondrocytes modulates hyaluronan expression and releasePublished

This page explains the topic in general terms; it does not tell anyone what treatment to follow.

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