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Wound healing
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Wound healing is the body's natural response to tissue injury, and it does not happen all at once: it goes through four overlapping phases that run into one another, namely hemostasis, inflammation, proliferation and remodeling. It is a construction job: stop the leak, clean up, build, finish.
The first thing is to stop the bleeding. The vessels constrict and the platelets aggregate, that is, they stick to one another. Then the inflammatory cells arrive, and the first one is the neutrophil, a type of white blood cell; once there they release cytokines, which are chemical messages between cells.
In proliferation, granulation tissue forms, the surface reepithelializes, that is, it grows a new covering, and new vessels grow. And as it remodels, the wound reaches its maximum strength.
In brief
Wound healing is the natural response to tissue injury and goes through four overlapping phases: hemostasis, inflammation, proliferation and remodeling.
It is a construction job: stop the leak, clean up, build, finish.
First the vessels constrict and platelets clump together to stop the bleeding; then inflammatory cells arrive, starting with the neutrophil, and release cytokines.
In proliferation, granulation tissue forms, the surface reepithelializes and vessels grow, and as the wound remodels it reaches its maximum strength.
Sources (2)
- National Center for Biotechnology Information, StatPearls PublishingWound Healing Phases, StatPearlsPublished
- National Center for Biotechnology Information, StatPearls PublishingPhysiology, Wound Healing, StatPearlsPublished
This page explains the topic in general terms; it does not tell anyone what treatment to follow.
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