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Bullous pemphigoid
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Bullous pemphigoid is an autoimmune skin disease in which a blister forms beneath the epidermis. Picture the skin's outermost layer lifting and leaving a space underneath: that space is the subepidermal blister.
Autoantibodies are immune proteins that recognize parts of the body's own tissues. In bullous pemphigoid, they may recognize BP180, also called BPAg2, and BP230, also called BPAg1. This response promotes blister formation.
In brief
Bullous pemphigoid is an autoimmune skin disease in which a subepidermal blister forms, meaning a blister below the epidermis.
In this disease, autoantibodies may recognize BP180, also called BPAg2, and BP230, also called BPAg1. This immune response promotes the formation of a subepidermal blister.
Sources (1)
- Merck Manual Professional EditionBullous Pemphigoid
This page explains the topic in general terms; it does not tell anyone what treatment to follow.
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