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Thyroid follicular cell
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A thyroid follicular cell takes iodide from the blood and concentrates it. Then, in the colloid, iodine attaches to tyrosines in thyroglobulin as one step in making thyroid hormones.
Picture many cuboidal cells arranged in a ring around a small space: together, they form a follicle. The space, or lumen, contains colloid, a material made mainly of thyroglobulin, a glycoprotein produced by these same cells.
In brief
Thyroid follicular cells take up and concentrate iodide from the blood. Then, within the colloid, iodine binds to tyrosines in thyroglobulin as part of thyroid hormone synthesis.
These cells form the simple cuboidal epithelial wall of thyroid follicles. They surround a lumen filled with colloid, which is composed mainly of thyroglobulin, a glycoprotein made by the follicular epithelium.
Sources (2)
- OpenStax, Rice University17.4 The Thyroid Gland
- Duke University School of Medicine, Department of PathologyDuke Histology: Endocrine System
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